Power Hour Surge: Biotech Cash Floods, Energy Breakouts, and AI Bets Drive the Stocks to Watch into the Close

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Today at 7:02pm UTC

Denver, Colorado – As Wall Street heads into the final stretch of the trading day, capital flows into biotech financing, clean energy, and emerging technology platforms are shaping the stocks traders are watching most closely into the close and after-hours session.

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Here’s the Power Hour watchlist and the stories driving today’s market action.

Energy Breakout: Permian Producer Hits New High

EON Resources (NYSE:EONR) is drawing attention after the independent energy company hit a new 52-week high of $1.25, signaling continued momentum in small-cap oil producers.

The company operates roughly 20,000 leasehold acres in the Permian Basin with about 750 producing and injection wells generating more than 1,000 barrels of oil per day.

Today’s catalyst: a risk-management move aimed at stabilizing future revenues. The company announced it is expanding its hedging program across 2026 and 2027, using forward contracts to help manage commodity volatility.

With crude prices remaining sensitive to geopolitical developments and supply dynamics, investors are watching whether Permian-focused operators like EONR can lock in pricing and extend their recent rally into the close.

Sustainable Aviation Fuel Story Builds

Another emerging energy narrative involves clean aviation fuels, and traders are watching XCF Global (NASDAQ:SAFX).

The company is positioning itself as an early mover in sustainable aviation fuel (SAF) production as airlines and regulators push toward net-zero emissions targets.

Its flagship New Rise Reno facility carries a permitted production capacity of 38 million gallons annually, giving the company a foothold in a market expected to expand rapidly over the next decade.

XCF is also advancing potential expansion projects in Nevada, North Carolina, and Florida, aiming to scale production and build partnerships across the aviation and energy sectors. With the global aviation industry racing to secure SAF supply chains, traders are watching whether SAFX gains momentum into after-hours trading.

Breakthrough Biomaterials Story Gains Attention

Advanced materials innovator Kraig Biocraft Laboratories (OTCQB:KBLB) is also drawing attention after reporting a key milestone in its “Project Atlas” bioengineering initiative.

The program is designed to combine multiple genetic modifications into a single integrated biological architecture capable of producing next-generation biomaterials with enhanced strength and durability.

CEO Kim Thompson described the work as “the most advanced molecular biology work ever undertaken in material science.”

The program has already generated new transgenic spider-silk lines that are now moving through the company’s evaluation pipeline, potentially expanding applications for defense materials, industrial textiles, and advanced composites.

The company’s growing visibility was recently underscored by a feature on the cover of the March issue of National Geographic highlighting advances in scalable spider-silk production.

Telehealth Stock Ignites Short Squeeze

One of today’s most dramatic moves belongs to Hims & Hers Health (NYSE:HIMS), which surged after reports of a potential partnership with Novo Nordisk (NYSE:NVO).

The reported deal could allow Novo Nordisk to distribute its obesity treatments through the Hims & Hers telehealth platform.

The rally is amplified by extremely high short interest, around 37% of the float, creating the conditions for a potential short squeeze as traders rush to cover positions.

The speculation comes after previous tensions between the companies over compounded semaglutide products, making the possible partnership a dramatic reversal that traders will continue monitoring into the close.

Oncology Platform Posts Encouraging Clinical Data

Biotech investors are also watching Medicus Pharma (NASDAQ:MDCX) following new analysis of its Phase 2 SKNJCT-003 study evaluating the SkinJect microneedle delivery system for basal cell carcinoma.

The study’s 200-µg treatment cohort showed 73% clinical clearance at Day 57, meaning the visible tumor disappeared in nearly three-quarters of treated lesions.

Executive Chairman and CEO Dr. Raza Bokhari said the results support advancing the therapy toward regulatory discussions, noting the data “reinforces the premise of SkinJect as a potential new treatment modality for basal cell carcinoma.”

Because basal cell carcinoma is the most common cancer worldwide, a minimally invasive treatment alternative to surgery could attract significant attention from dermatology and oncology partners.

Biotech Financing Wave Continues

Capital raising activity is another dominant theme late in the session, with several biotech firms securing major funding rounds.

  • Relmada Therapeutics (NASDAQ:RLMD) announced an oversubscribed $160 million PIPE financing backed by leading healthcare investors including RA Capital Management and OrbiMed.

  • Solid Biosciences (NASDAQ:SLDB) secured an oversubscribed $240 million private placement to fund development of genetic medicines for neuromuscular and cardiac diseases.

  • AN2 Therapeutics (NASDAQ:ANTX) priced a $40 million private placement to advance its boron-chemistry-based small-molecule drug platform.

The string of financings signals renewed institutional appetite for clinical-stage biotech, particularly companies advancing novel therapeutic platforms.

Gene Editing Milestones Keep Investors Watching

Meanwhile, gene-editing pioneer Editas Medicine (NASDAQ:EDIT) reported progress on EDIT-401, an in-vivo gene-editing therapy aimed at treating heterozygous familial hypercholesterolemia.

The therapy has demonstrated more than 90% mean LDL cholesterol reduction in preclinical studies, and the company remains on track to file an IND by mid-2026 and launch its first human clinical trial later this year.

Management says the company’s cash runway extends into the third quarter of 2027, providing funding for the next major clinical milestones.

Additive Manufacturing Rebounds in Key Markets

Industrial technology company 3D Systems (NYSE:DDD) is also in focus after reporting fourth-quarter results.

Revenue reached $106.3 million, rising 16% sequentially, driven by stronger printer sales and materials demand.

CEO Jeffrey Graves said med-tech, dental, and aerospace and defense markets are increasingly adopting additive manufacturing as a core production method, areas the company believes could deliver sustained growth over the next decade.

For more information about Kraig Labs’ spider silk technology and partnership opportunities, visit www.kraiglabs.com

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NYSE:EONR, NASDAQ:SAFX, OTCQB:KBLB, NYSE:HIMS, NASDAQ:MDCX, NASDAQ:ANTX