Denver, Colorado- Markets open with a clear signal from the micro- and small-cap arena: intellectual property, regulatory momentum, and platform scalability are driving value creation well ahead of broad risk appetite.
BriaCell Therapeutics (NASDAQ:BCTX): Durable Response Strengthens Immunotherapy Case
BriaCell reported 11-month sustained complete resolution of a lung metastasis in a patient treated with Bria-OTS
in its Phase 1/2a metastatic breast cancer study. The response, observed without treatment-limiting toxicities, reinforces the therapeutic potential of Bria-OTS as the program advances into Phase 2a combination cohorts with checkpoint inhibitors.
Durability remains a key differentiator in oncology, and extended complete responses, particularly in heavily pretreated patients, are closely watched signals as programs move up the development curve.
Kraig Biocraft Laboratories (OTCQB:KBLB): Spider Silk Reaches Industrial Scale
Kraig Labs reached a critical operational milestone with the completion of its third silkworm rearing facility, enabling three concurrent production cycles and targeting output exceeding one metric ton of recombinant spider silk per month.
This development caps a multi-year transition from laboratory consistency to repeatable, industrial-scale production, positioning Kraig as one of the few companies globally capable of producing spider silk at commercial volumes. With vertically integrated mulberry cultivation and expanded capacity coming online this quarter, Kraig is moving decisively from materials science promise to scalable manufacturing reality.
XTL Biopharmaceuticals (NASDAQ:XTLB) & Beyond Air (NASDAQ:XAIR): Targeting Autism at the Molecular Level
XTL Biopharmaceuticals announced a binding agreement to acquire 85% of NeuroNOS, a Beyond Air subsidiary developing disease-modifying therapeutics for Autism Spectrum Disorder (ASD) and neuro-oncology. The transaction positions XTL at the center of a massive unmet medical need, as autism now affects approximately 1 in 31 U.S. children, with no FDA-approved disease-modifying treatments available.
NeuroNOS’s platform targets nitric oxide dysregulation, a core biological pathway implicated in autism and brain cancer, and already holds FDA Orphan Drug Designations for Phelan-McDermid Syndrome and Glioblastoma. Beyond Air will retain 19.99% ownership in XTL and is eligible for milestone payments of up to $32.5 million, aligning incentives as the program advances toward the clinic.
CytoMed (NASDAQ:GDTC): Capital Discipline Meets Cell Therapy Progress
CytoMed Therapeutics entered 2026 emphasizing capital efficiency and pipeline diversification, supported by its Southeast Asia manufacturing footprint. The company continues to advance both gamma delta (γδ) T-cell and Natural Killer (NK) cell therapies, with multiple first-in-human studies underway or planned across Singapore and Malaysia.
With sufficient funding runway for at least the next year, government support for NK cell development, and active discussions around licensing and asset monetization, CytoMed highlights an alternative biotech model—lower-cost clinical execution paired with strategic partnerships to minimize dilution.
Fortress Biotech (NASDAQ:FBIO): FDA Approval Unlocks Rare-Disease Value
Fortress Biotech and its subsidiary Cyprium Therapeutics secured FDA approval of ZYCUBO®, the first and only approved treatment for Menkes disease in the United States. The approval includes a Rare Pediatric Disease Priority Review Voucher, transferable to Cyprium, and eligibility for up to $129 million in milestones plus tiered royalties.
The decision adds to Fortress’s growing list of recent FDA approvals and validates its portfolio-based model, where late-stage execution and strategic monetization coexist across rare disease, oncology, and immunology assets.
Decoy Therapeutics (NASDAQ:DCOY): Designing for Global Scale
Decoy Therapeutics announced progress under its Global Access Commitment Agreement with the Gates Foundation, focused on building a globally accessible, scalable manufacturing platform for peptide-conjugate antivirals using its IMP3ACT platform.
By prioritizing “design-for-manufacturing,” Decoy aims to reduce cost and complexity while enabling rapid response to emerging pathogens. The platform will be validated through a pan-coronavirus intranasal antiviral program, with an IND filing targeted within 12 months, highlighting how global health initiatives can also reinforce long-term commercial readiness.
About Kraig Biocraft Laboratories, Inc.
Kraig Biocraft Laboratories, Inc. (OTCQB: KBLB) is a biotechnology company focused on the development and commercialization of spider silk-based fiber technologies. Through its proprietary silkworm-based genetic engineering platform, Kraig Labs produces high-performance, cost-effective, and scalable spider silk materials for use in defense, performance apparel, technical textiles, and medical applications.
For more information, please visit: www.kraiglabs.com
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Cautionary Note Regarding Forward-Looking Statements
This press release contains forward-looking statements that are subject to various risks and uncertainties. Such statements include statements regarding the Company’s ability to grow its business and other statements that are not historical facts, including statements which may be accompanied by the words “intends,” “may,” “will,” “plans,” “expects,” “anticipates,” “projects,” “predicts,” “estimates,” “aims,” “believes,” “hopes,” “potential” or similar words. Actual results could differ materially from those described in these forward-looking statements due to a number of factors, including without limitation, the Company’s ability to continue as a going concern, general economic conditions, and other risk factors detailed in the Company’s filings with the SEC. The forward-looking statements contained in this press release are made as of the date of this press release, and the Company does not undertake any responsibility to update such forward-looking statements except in accordance with applicable law.